INFECTIVE ENDOCARDITIS UPDATE AHA 2015

  • Recommendations

     

  • A 4-week regimen of intravenous aqueous crystalline penicillin G (or ampicillin if penicillin G isunavailable) achieves a high cure rate in those withhighly penicillin-susceptible streptococcal IE.112 This approach avoids aminoglycoside-containingregimens for children with impairment of renal function, concurrently administered nephrotoxicdrugs, or eighth cranial nerve impairment. In adult patients, 4 weeks of therapy with ceftriaxone given once daily also is a recommended approach113 (Class I; Level of Evidence B).
  • Although home treatment for part of the antibioticcourse appears to be becoming a more            frequently sed option, this decision is reasonable but requires careful selection of the appropriate candidate based          on family accommodations and access to home healthcare providers (Class IIa; Level of Evidence B).
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About Dr. Jayaprakash

Asst. Prof. of Pediatrics, ICH. Institute of Child Health. Gov. Medical College Kottayam. Kerala, India.

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