- Recommendations
- A 4-week regimen of intravenous aqueous crystalline penicillin G (or ampicillin if penicillin G isunavailable) achieves a high cure rate in those withhighly penicillin-susceptible streptococcal IE.112 This approach avoids aminoglycoside-containingregimens for children with impairment of renal function, concurrently administered nephrotoxicdrugs, or eighth cranial nerve impairment. In adult patients, 4 weeks of therapy with ceftriaxone given once daily also is a recommended approach113 (Class I; Level of Evidence B).
- Although home treatment for part of the antibioticcourse appears to be becoming a more frequently sed option, this decision is reasonable but requires careful selection of the appropriate candidate based on family accommodations and access to home healthcare providers (Class IIa; Level of Evidence B).
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Dr. Jayaprakash
Superintendent, ICH.
Institute of Child Health.
Gov. Medical College Kottayam.
Kerala, India.